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Abstract Insulin-like growth factor-1 (IGF-1) is a pleiotropic protein hormone and has become an attractive therapeutic target because of its multiple roles in various physiological processes, including growth, development, and metabolism

Life Sci Alliance 2021, 4(7)

Davidovic ZS, Miljkovic GM, Antonovic GD, Rajilic-Stojanovic DM, Dimitrijevic-Brankovic IS

Serafini M, Peluso I

In addition, dysbiosis may produce new epitopes with auto-immunogenicity through post-translational modification of proteins, including citrullination and acetylation of active lysine, etc., and then induce autoimmune reactions [77]

The study was conducted after approval of the Ethical Committee of Ain Shams University Hospitals under acceptance number FMASU M D 199/ 2021 and was registered in clinicaltrials.gov, identifier number NCT05371184